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Short bowel syndrome (SBS, also short gut syndrome or simply short gut) is a malabsorption disorder caused by the surgical removal of the small intestine, or rarely due to the complete dysfunction of a large segment of bowel. Most cases are acquired, although some children are born with a congenital short bowel. It usually does not develop unless more than two thirds of the small intestine have been removed. SBS has been designated a rare disease by the EMA, and is eligible for orphan drug designation according to the U.S. Food and Drug Administration (FDA). There are roughly 3,500 adults and 9,000 children with SBS in the USA alone. ==Signs and symptoms== The symptoms of short bowel syndrome can include: * Abdominal pain * Diarrhea and steatorrhea (oily or sticky stool, which can be malodorous) * Fluid depletion * Weight loss and malnutrition * Fatigue Patients with short bowel syndrome may have complications caused by malabsorption of vitamins and minerals, such as deficiencies in vitamins A, D, E, K, B9 (folic acid), and B12, calcium, magnesium, iron, and zinc. These may appear as anemia, hyperkeratosis (scaling of the skin), easy bruising, muscle spasms, poor blood clotting, and bone pain. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Short bowel syndrome」の詳細全文を読む スポンサード リンク
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